Application Bibliography
Application | Area Product | Reference | Date |
---|---|---|---|
Immunofluorescence identification of metastatic prostate cancer cells based on epithelial cell adhesion molecule (EpCAM) expression | Diagnostics SOLA Light Engine | A magnetic microneedle to isolate single immunomagnetically labeled cells. Lab Chip (2024) 24:460–466 M Stevens, P Harder, LWMM Terstappen | 2024 |
Imaging laminar flow of peripheral blood mononuclear cells (PBMC) and neutrophils during microfluidic acoustophoresis | Microfluidics CELESTA Light Engine | Label‐free separation of peripheral blood mononuclear cells from whole blood by gradient acoustic focusing. Sci Rep (2024) 14:8748 J Alsved, MR Charan, P Augustsson et al. | 2024 |
Imaging fission and fusion of neuronal mitochondria expressing photoactivatable GFP (paGFP) and mScarlet | Live Cell Microscopy AURA Light Engine | 2024 | |
In situ sequencing (ISS) for single-cell spatial expression profiling of the spatiotemporal cellular dynamics underlying autoimmune encephalomyelitis (EAE) evolution. | Transcriptomics SPECTRA X Light Engine | Cellular architecture of evolving neuroinflammatory lesions P Kukanja, CM Langseth, G Castelo-Branco et al. | 2024 |
Real-time measurement of polymer–nucleotide substrate (avidite) binding to DNA polonies | Genomic Analysis RETRA Light Engine | Sequencing by avidity enables high accuracy with low reagent consumption. Nat Biotechnol (2024) 42:132–138 S Arslan, FJ Garcia, M Previte et al. | 2024 |
Immunofluorescence detection of long myosin light-chain kinase (MLCK) splice variants in FFPE ileal tissue microarrays from Crohn’s disease patients. | Pathology SOLA Light Engine, AURA Light Engine | 2024 | |
Imaging intracellular neuropeptide concentrations using a genetically encoded sensor comprising vasoactive intestinal peptide receptor VPAC1 coupled to circularly permuted GFP | Pathology SPECTRA Light Engine, SPECTRA X Light Engine | Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature (2024) 627:149–156 MH Murdock, CY Yang, LH Tsai et al. | 2024 |
Vesicular glutamate transporter 1 (VGLUT1) mRNA FISH for identification and somal size measurement of human brain pyramidal neurons (PNs) | Fluorescence in Situ Hybridization (FISH) SPECTRA Light Engine | Scaling of smaller pyramidal neuron size and lower energy production in schizophrenia. Neurobiol Dis (2024) 191:106394 KE Schoonover, NE Miller, D Lewis et al. | 2024 |
Tracing interactions of polycomb group (PcG) proteins with chromatin by Optical Reconstruction of Chromatin Architecture (ORCA) | Transcriptomics CELESTA Light Engine | 2024 | |
Colocalization of antisense oligonucleotides and proteins using widefield 3D deconvolution microscopy | Immunofluorescence Microscopy AURA Light Engine | Profiling the interactome of oligonucleotide drugs by proximity biotinylation. Nat Chem Biol (2024) doi: 10.1038/s41589-023-01530-z A Hanswillemenke, DT Hofacker, T Stafforst | 2024 |
Structured illumination microscopy with 100 nm lateral and 300 nm axial resolution | Superresolution Microscopy CELESTA Light Engine | Easy access to super-resolution applications with DeepSIM. Microscopy Today (2024) 32, 10–15 C Brighi, L Clario, S Romanzi | 2024 |
Live-cell imaging for assessment of bacterial phenotype after antibiotic treatment | Microbiology SOLA Light Engine | 2024 | |
Immunofluorescence detection of anti-inflammatory CD8+ T cells in proximity to plaque-associated microglia in human and mouse Alzheimer’s disease brain tissue | Pathology SOLA Light Engine | 2023 | |
Single cell measurements of secreted antibody affinity for the SARS-CoV-2 spike receptor binding domain | Microfluidics AURA Light Engine | 2023 | |
Illuminatation (650 nm, 34 mW/cm2) of phosphorus-doped silicon (p–Si) photoelectrodes. | Materials Science SPECTRA Light Engine | 2023 | |
Detection of mechanosensory conformational rearrangements of PIEZO channels in HEK cells using cpGFP fluorescence | Microfluidics SPECTRA X Light Engine | 2023 | |
Characterization of hydrogenated amorphous silicon (a-Si:H) photoactivated switches | Materials Science MIRA Light Engine | Dynamic control of high-voltage actuator arrays by light-pattern projection on photoconductive switches. Microsyst Nanoeng (2023) 9:59 V Bacheva, A Firouzeh, G Kaigala et al. | 2023 |
Optical pooled screening (OPS) for identification of regulators of innate immune responses to RNA virus infection | High-Content Screening CELESTA Light Engine | A genome-wide optical pooled screen reveals regulators of cellular antiviral responses. Proc Natl Acad Sci U S A (2023) 120:e2210623120 RJ Carlson, MD Leiken, PC Blainey et al. | 2023 |
High-speed imaging of calcium transients in engineered heart tissues (EHTs) | Bioengineering SOLA Light Engine | 2023 | |
Temporally multiplexed imaging (TMI) using reversibly photoswitchable fluorescent proteins | Microscopy Technique Development SPECTRA X Light Engine | Temporally multiplexed imaging of dynamic signaling networks in living cells. Cell (2023) 186:1–17 Y Qian, OT Celiker, ES Boyden et al. | 2023 |
3D live-cell super-resolution imaging using enhanced super-resolution radial fluctuation (eSRRF) combined with multifocus microscopy (MFM) | Superresolution Microscopy SPECTRA Light Engine | 2023 | |
Imaging of genetically encoded voltage indicator (GEVI) JEDI-1P in dissociated rat cortical and hippocampal neurons | Live Cell Microscopy SPECTRA X Light Engine | 2023 | |
Maximum a posteriori probability structured illumination microscopy (MAP-SIM) of GFP–labeled coronal mouse brain slices | Superresolution Microscopy SPECTRA X Light Engine | 2023 | |
Spinning-disk confocal imaging of DAPI (405 nm), Alexa Fluor 488 phalloidin (477 nm) and FM4-64 (546 nm) in Naegleria gruberi and Dictyostelium discoideum. | Confocal Microscopy CELESTA Light Engine | A conserved pressure-driven mechanism for regulating cytosolic osmolarity. KB Velle, RM Garner, LK Fritz-Laylin et al. | 2023 |
Imaging of GFP-tagged synaptic proteins in C. elegans | Intravital Imaging SPECTRA X Light Engine | 2023 |